The carvings on the outside, which describe the Necromorph DNA, are basically a hazardous material warning, complete with a detailed description of the contents, and which human researches only tend to be able to partially translate (continually missing some of the important bits, like "Recommended Containment Protocols" and "Why you shouldn't let this get loose"). For whatever reason, these precursors couldn't or wouldn't destroy the Black Marker, and instead, they sealed it away on Earth- modifying it with the external carvings, the base, and some other things which create the Dead Space effect and the additional psychic effects (see below).
The Marker is Sealed Evil in a Leaky CanSo, however many millennium ago, the Black Marker and it's Necromorph-generating properties existed, and was fought against by some form of precursors.
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